Major advances in software technologies will be required to enable the "new Internet." Areas of investigation will include large-scale, ad hoc wireless networks, a secure metacomputing infrastructure, mobile agent technologies, sensor simulation, sensor network integration, and development of new middleware and human-computer interfaces. The need for innovation in algorithms to match the vast size and complexity of this new Internet, in turn, indicates that mathematical research will also play a critically important role in our institute. UCSD will take the lead in this layer with strong collaboration from UCI's Information and Computer Science Department, Center for Networks and Middleware Information Systems, and Center of Integrated Information Technologies for Infrastructure Systems. Underlying all Calit2 software infrastructure development will be the need for security and scalability.

• ActiveCampus
• Advanced Engineering Methods for Networked Automotive Software
• BioNet
• Center for GRAVITY
• Citizen Awareness System for Crisis Mitigation [CAMAS]
• Collaborative Center for Internet Epidemiology and Defenses [CCIED]
• Distributed Image and Information Processing for Automated Monitoring [Smart Vivarium]
• Earth and Planetary Science Game Engine [EPSS-GE]
• GEON: The Geosciences Network [GEON]
• Institute for Genomics and Bioinformatics [IGB]
• Institute for Software Research [ISR]
• Integration of Multi-Source Data
• Network Systems Center [NSC]
• Reconfigurable Ubiquitous Networked Embedded Systems [RUNES]
• Responding to Crises and Unexpected Events [RESCUE]
• ResponSphere
• The Virtual Raft
• Traces Vision System
• VizClass

• Center for Embedded Computer Systems (UCI)
• Institute for Software Research (UCI)
• Center for Pervasive Communications and Computations (UCI)